Clinical Studies

Credible Research-Incredible Results

The effectiveness of the AutoPulse® cardiac support pump is supported by a growing body of objective third-party research.

Krep H et al.  Out-of-hospital cardiopulmonary resuscitation with the AutoPulse system: a prospective observational study with a new load-distributing band chest compression device. Resuscitation. 2007;86:86-95.

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Animal Hemodynamics Study 1
AutoPulse produced pre-arrest levels of
blood flow to the heart and brain.

Human Hemodynamics Study 2
AutoPulse-generated CPP was 33%
better than manual CPR.

Animal Survival Study 3
73% of the subjects supported with AutoPulse returned to normal blood flow and survived; 88% were neurologically normal.

0% of the subjects supported with only conventional CPR survived.

Human Short-term Survival Study 4
AutoPulse improved field ROSC rate by 74%, regardless of the initial rhythm.
Human Short-term Survival Study 5
AutoPulse improved the rate of delivery
of patients in ROSC sustained to the
ED by 35%.
% Survival Autopulse vs Manual CPR
AutoPulse Survival Rates6
AutoPulse tripled survival to hospital discharge

1. Halperin HR et al. Improved hemodynamics with a novel chest compression device during a porcine model of cardiac arrest. Circulation. 2002;106(19)(Suppl II):538.

2. Timerman S et al. Improved hemodynamic performance with a novel chest compression device during treatment of in-hospital cardiac arrest. Resuscitation. 2004;61:273-280.

3. Ikeno F et al. Improved survival with a novel chest compression device during a porcine model of cardiac arrest. Circulation. 108(17)(Suppl IV):381.

4. Ornato JP et al. Improvement in field return of spontaneous circulation using circumferential chest compression cardiopulmonary resuscitation. Prehospital Emergency Care. 9(1):104.

5. Casner M et al. The impact of a new CPR assist device on rate of return of spontaneous circulation in out-of-hospital cardiac arrest. Prehospital Emergency Care. 9(1):61-67.

6. Ong et al. Use of an automated, load-distributing band chest compression device for out-of-hospital cardiac arrest resuscitation. JAMA. 2006;295:2629-2637.